A non-invasive method to evaluate gastrointestinal transit behavior in rat

A non-invasive method to evaluate gastrointestinal transit behavior in rat.

INTRODUCTION Many factors alter gastrointestinal transit. Animal models are useful for preclinical studies of gastrointestinal transit, but terminal methods do not allow later study, and stressful assessment methods will likely alter the transit of the animal. To overcome these factors, we developed a new method to assay rat total gastrointestinal transit. METHODS Standard plastic cages with ...

Effects of Artemisia dracunculus essential oil on diarrhea and intestinal transit time in rat gastrointestinal tract

Introduction: Artemisia dracunculus L. belongs to Asteraceae family, and is a medicinal plant widely used in traditional medicine as a remedy for gastrointestinal disturbances. This study was undertaken to evaluate the effects of essential oil of A. dracunculus (EOAD) on the rat alimentary tract. Methods: The EOAD was extracted by Clevenger apparatus using hydrodistillation. LD50 was calcula...

Electrochemical Basis for EZSCAN/SUDOSCAN: A Quick, Simple, and Non-Invasive Method to Evaluate Sudomotor Dysfunctions

Stress effects on gastrointestinal transit in the rat.

Previous investigations of stress effects on gastric emptying, orocaecal, and colonic transit in rats have produced conflicting results. Here one type of stressor, a 'passive avoidance' situation, was used to investigate its effects on gastric emptying, orocaecal and colonic transit. After the rats had been trained to eat a standard amount of semisolid food, gastric emptying was determined (n =...

Non-invasive measurement of skin autofluorescence to evaluate diabetic complications.

Although the accumulation of advanced glycation end-products (AGEs) of the Maillard reaction in our body is reported to increase with aging and is enhanced by the pathogenesis of lifestyle-related diseases such as diabetes, routine measurement of AGEs is not applied to regular clinical diagnoses due to the lack of conventional and reliable techniques for AGEs analyses. In the present study, a n...